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The human placenta produces inflammation inducing substances

Russian scientists have determined which cells of the human placenta secrete compounds of the class of interleukins-17 (IL-17, they are also known as cytokines-17). The scientists came to a conclusion that the function is performed by placental macrophages. The way and timing of release of interleukin-17 by placenta macrophages suggest that it can be assumed that they play a role not only in immune processes, but also in the development of a 'child's place'. The results of the study are available in the article published by the American Journal of Reproductive Immunology.
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It can be added that innterleukins-17 also induce inflammatory processes and regulate growth of new blood vessels in the placenta.

Another hypothesis concerning the role of innterleukins-17, isolated by placental macrophages, presumes that they «teach» the immune cells of the mother’s body. IL-17 A и IL-17 F can enter the main bloodstream of the pregnant woman via the vessels of the umbilical cord, where they could 'meet' macrophages and other types of cells bearing a sufficient number of receptors for interleukins-17. As a result, the mother’s immune system is able to better cope with the pathogens attacking it and better protect both the woman and her unborn child.

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