Russian scientists have studied the structure of regenerating cardiac tissue
For the regeneration of the heart tissues a substrate — a matrix of polymer fibers — is used, on which heart cells (cardiomyocytes) and connective tissue (fibroblasts) grow. It is necessary to know how the components of the regenerating tissue interact with each other in order to select the nanofibres for the substrate.
Russian scientists studied the interaction of a substrate of polymer fibers with heart cells of a rat.
It turned out that fibroblasts have a more rigid structure and a smaller area of interaction with nanofibres, and touch them only on one side. Cardiomyocytes, when grown on a substrate, envelop nanofibers from all sides and stick to the substrate better.
This gives the bioengineers a better understanding of the properties of the regenerating tissue and the ability to make it more efficient.