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Scientists have found the origin of obesity in stem cells

Researchers at the Moscow State University described a new mechanism which possibly underlines the development of obesity. They found a group of stem cells which actively transform into fat cells under the action of a hormone called angiotensin II.
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Scientists have investigated the effect of angiotensin II on stem cells during the process of their specialization — these «universal» cells have the ability to become any type of cell.

In the course of the experiments, Russian scientists identified a group of stem cells which are particularly actively converting into fat cells (adipocytes) when under the action of the hormone. This group of cells shows particularly strong reaction to the hormone, speeding up the process of specialization. The authors of the paper believe that such an intensive differentiation of these cells can underlie disturbances in the formation of adipose tissue, leading to obesity.

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