Russian scientists embraced measuring speed of moving erythrocytes through capillaries
The investigation of shape and state of capillaries is an efficient way to estimate the state of the blood-vascular system in general. However, one of the key parameters — the speed of transfer of blood and blood corpuscles, still represents a challenge for direct measurements. For the first time, the Russian scientists have met the challenge and developed an exclusive system of video recording with a high space-temporal resolution.
The system includes a microscope, high-speed camera, and computer algorithms of treatment and analysis of obtained data which are capable of determining the shape and sizes of each particular capillary and track the speed of moving erythrocytes along its central line.
«Although the device is relatively simple, it can help in getting objective diagnostics characteristics and fix the trends of appearing a pathology. Moreover, it is painless, non-hazardous, and comfort for a subject procedure,» - the principal author of the development from ITMO University said.
Indeed, the blood supply of biological tissues serves as one of the essential factors of its state. Furthermore, in the case of some pathologies, the state of blood vessels might remain in the normal conditions on the outside. Therefore, the key and objective characteristics of the blood flow should be the speed of the transfer of erythrocytes. All other approaches could either could not provide a precise and reliable picture or do now allow for long measurements in selected capillaries.
The article summarizing the results of the study has been published in the journal Optics and Lasers in Engineering.
Previously, the researchers from the Institute of Biology from Irkutsk State University together with colleagues from Finland and Singapore created microsensors which start fluorescing upon the changes of blood acidity.