Russian biologists have found a way to lower blood sugar level
Researchers at the Institute of Cytology of the Russian Academy of Sciences (St. Petersburg) and their colleagues from the University of Turku (Finland) have shown that the accelerated exchange of glycogen leads to the development of prediabetes — a steady increase in the glucose level in the blood. They used mice as the experimental animals. A drug called metformin, which acts on the structure of glycogen, could help make glucose levels closer to the norm. A scientific article is published in the British Journal of Pharmacology.
Metformin is one of the drugs often used to treat diabetes mellitus, it affects the processes that lead to insulin resistance of liver cells and increase the intensity of glucose formation from compounds that are not sugars.
The experiment on mice showed that metformin reduces the intensity of «assembly-disassembly» of glycogen molecules and thus reduces the sugar content in the blood.
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