Russian biochemists have found the cause of the ineffectiveness of the vaccine against influenza
The results of the experiment led the authors to the conclusion that the standard vaccine against influenza practically does not enhance the ability of the human immune system to cope with the causative agent of the disease, since it does not significantly change the TCR repertoire. However, it is possible that each vaccine still leaves behind a «memory» of the antigens encountered. But since the composition of proteins on the surface of influenza viruses changes rapidly due to frequent mutations in the coding genes, information about them almost immediately becomes obsolete and therefore useless for the immune system.
The authors of the article now plan to conduct a study on a larger number of volunteers in order to verify the results obtained.