Russian scientists began work on correction of gene mutations in patients with cystic fibrosis
«We have obtained skin epithelial cells of patients over 18 years of age; these are patients with the most common among the most severe mutations,» Smirnikhina said. She farther explained that scientists correct mutations in them with the help of special methods of reprogramming of cells. The experiments are carried out using modifications developed in the laboratory of the Russian centre.
Smirnikhina added that there is no effective and affordable pathogenetic treatment aimed at blocking the development of disease mechanisms. «Life expectancy of patients with severe genetic mutations often does not exceed 25 years,» she noted.